Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510831 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10508099 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL570203 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10506976 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL2117269 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10735194 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL570204 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL3060848 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10508715 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10506819 | 0.94 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173462-B1 | ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF | SUNTORY LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4698423-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0173462-A2 | Ellipticine derivative and production process thereof | SUNTORY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |