Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510831 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10508099 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL570203 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10506976 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL2117269 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10735194 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL570204 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10508209 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10508715 | 1.00 | TSHR (0.41) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10506819 | 0.94 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608045-A | DISODIUM SALT BY POT REACTING RHAMNOSE TRIACETATE WITH PHENYL DICHLOROPHOSPHATE IN PRESENCE OF TRIETHYLAMINE AND WITH /S/LEU-/S/TRP-OET IN SOLVENT, SAPONIFYING SEPARATED PRODUCT WITH ETHANOLIC BASE IN COLD, EVAPORATING ETHANOL | ADIR ET COMPAGNIE (FR) | 1997-03-04 | — | — | US | claimed |
| CN-103781472-B | Synthesis and use of propofol glycoside derivatives | 纽泰克制药有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103781472-A | Synthesis and use of propofol glycoside derivatives | NUTEK PHARMA LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-103702670-A | Synthesis and use of glycoside pro-drug analogs | NUTEK PHARMA LTD | 2014-04-02 | — | — | CN | disclosed |
| US-8278436-B2 | Glycosylated warfarin analogs and uses thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100267655-A1 | Glycosylated Warfarin Analogs and Uses Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-10-21 | — | — | US | disclosed |
| US-5608045-A | DISODIUM SALT BY POT REACTING RHAMNOSE TRIACETATE WITH PHENYL DICHLOROPHOSPHATE IN PRESENCE OF TRIETHYLAMINE AND WITH /S/LEU-/S/TRP-OET IN SOLVENT, SAPONIFYING SEPARATED PRODUCT WITH ETHANOLIC BASE IN COLD, EVAPORATING ETHANOL | ADIR ET COMPAGNIE (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5591728-A | ENZYME INHIBITORS WITH AMIDE AND ESTER GROUPS | ADIR ET COMPAGNIE (FR) | 1997-01-07 | — | — | US | disclosed |
| US-5481030-A | USED AS AN ENDOTHELIN CONVERTASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1996-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267655-A1 | Glycosylated Warfarin Analogs and Uses Thereof | GPI, UGGT1, GALE | TSHR 2519/4885TDP1 3781/4885CHRM2 3924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.