SCHEMBL10508239

SCHEMBL10508239

CCC(C)Oc1cc2c(cc1OC)C=CC(C)(C)O2

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.46
EPAS1 Q99814 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10508119 0.87 ODC1 (0.46) HIF1AEPAS1
Prococene Ii SCHEMBL119925 0.85 ODC1 (0.54) HIF1AEPAS1
SCHEMBL10508738 0.81 TLR3 (0.49) HIF1AEPAS1
SCHEMBL10510924 0.80 TLR3 (0.53) HIF1AEPAS1
SCHEMBL119216 0.80 TLR3 (0.53) HIF1AEPAS1
Prococene Ii SCHEMBL1070896 0.80 TLR3 (0.53) HIF1AEPAS1
SCHEMBL10508060 0.78 TLR3 (0.51) HIF1AEPAS1
SCHEMBL10507476 0.77 ODC1 (0.47) HIF1A
SCHEMBL10507493 0.77 TLR3 (0.50) HIF1AEPAS1
SCHEMBL11012720 0.76 TLR3 (0.48) HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129636-B1 PROCESS FOR THE PREPARATION OF CHROMEN DERIVATIVES ALKALOIDA VEGYéSZETI GYáR (HU) 1989-01-04 EP disclosed