SCHEMBL10508307

SCHEMBL10508307

CCCCN=NCC(C)(CC(C)C#N)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1659729 0.87 TSHR (0.30)
SCHEMBL7758034 0.80
SCHEMBL5172097 0.78
SCHEMBL10699351 0.70 PPARA (0.33)
SCHEMBL7561709 0.70 TSHR (0.36)
SCHEMBL7561715 0.70 TSHR (0.36)
SCHEMBL8755752 0.70 TSHR (0.41)
SCHEMBL10508302 0.70
SCHEMBL29195957 0.66
SCHEMBL225684 0.65 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3325140-A1 CONTINUOUS ADIABATIC INVERSE EMULSION POLYMERIZATION PROCESS Technology Investment & Development, LLC (US) 2018-05-30 EP disclosed
WO-2017019471-A1 CONTINUOUS ADIABATIC INVERSE EMULSION POLYMERIZATION PROCESS Technology Investment & Development, LLC (US) 2017-02-02 WO disclosed
US-4834922-A DECARBOXYLATION THE DOW CHEMICAL COMPANY (US) 1989-05-30 US disclosed
EP-0312920-A2 Flexible flame resistant polyurethane foams BASF Corporation (US) 1989-04-26 EP disclosed
US-4804727-A Process to produce novel fluorocarbon vinyl ethers and resulting polymers THE DOW CHEMICAL COMPANY (US) 1989-02-14 US disclosed
US-4687821-A PERHALO VINYL ALKYL ETHERS THE DOW CHEMICAL COMPANY (US) 1987-08-18 US disclosed
EP-0072579-B1 PREPARATION OF FLUORINATED ACID FLUORIDES THE DOW CHEMICAL COMPANY (US) 1985-07-17 EP disclosed
US-4515989-A FLUOROPOLYMERS THE DOW CHEMICAL COMPANY (US) 1985-05-07 US disclosed
EP-0041737-B1 PROCESS TO PRODUCE NOVEL FLUOROCARBON VINYL ETHERS AND RESULTING POLYMERS THE DOW CHEMICAL COMPANY (US) 1984-08-29 EP disclosed
EP-0073069-A1 Method of polymerizing vinyl ethers THE DOW CHEMICAL COMPANY (US) 1983-03-02 EP disclosed
EP-0072579-A1 Preparation of fluorinated acid fluorides THE DOW CHEMICAL COMPANY (US) 1983-02-23 EP disclosed
EP-0041737-A1 Process to produce novel fluorocarbon vinyl ethers and resulting polymers THE DOW CHEMICAL COMPANY (US) 1981-12-16 EP disclosed
EP-0041739-A2 Preparation of fluorinated acid fluorides; preparation of acids, amides or esters derived therefrom, copolymerization of fluorinated vinyl ethers THE DOW CHEMICAL COMPANY (US) 1981-12-16 EP disclosed
US-4260548-A INCREMENTAL ADDITION OF FREE RADICAL CATALYST PRINCETON POLYMER LABORATORIES (US) 1981-04-07 US disclosed