Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950479 | 0.89 | MOGAT2 (0.43) | MOGAT2MEN1KMT2ACNR2CHRM3 | |
| SCHEMBL9678523 | 0.88 | MEN1 (0.48) | MOGAT2MEN1KMT2ACNR2CHRM2 | |
| Hydrochloric Acid SCHEMBL10508673 | 0.87 | MOGAT2 (0.42) | MOGAT2MEN1KMT2ACNR2USP30 | |
| Hydrochloric Acid SCHEMBL10508668 | 0.87 | MOGAT2 (0.42) | MOGAT2MEN1KMT2ACNR2USP30 | |
| Hydrochloric Acid SCHEMBL9642007 | 0.87 | MEN1 (0.47) | MOGAT2MEN1KMT2ACNR2CHRM2 | |
| SCHEMBL10506690 | 0.84 | CNR2 (0.45) | MOGAT2CNR2CHRM2HTR1ADRD3 | |
| SCHEMBL9770892 | 0.81 | AVPR1B (0.38) | MEN1KMT2ACHRM3 | |
| SCHEMBL10506452 | 0.81 | CNR2 (0.43) | MOGAT2MEN1KMT2ACNR2LTA4H | |
| SCHEMBL10506508 | 0.81 | CNR2 (0.43) | MOGAT2MEN1KMT2ACNR2CHRM2 | |
| SCHEMBL10506500 | 0.81 | CNR2 (0.42) | MOGAT2MEN1KMT2ACNR2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140359-B1 | MORPHOLINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1989-01-25 | — | — | EP | claimed |
| EP-0140359-A1 | Morpholine derivatives | BEECHAM GROUP PLC (GB) | 1985-05-08 | — | — | EP | claimed |