Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770829 | 0.86 | ADRB2 (0.38) | AVPR1BCHRM3ADRB1ADRB3DRD4 | |
| SCHEMBL9770863 | 0.84 | ADRB2 (0.39) | AVPR1BCHRM3ADRB1ADRB3DRD4 | |
| SCHEMBL9770814 | 0.83 | GLA (0.40) | AVPR1BCHRM3ADRB1ADRB3DRD4 | |
| SCHEMBL9770894 | 0.82 | AVPR1B (0.38) | AVPR1BADRB1ADRB3MEN1ALDH1A1 | |
| SCHEMBL9770796 | 0.82 | ADRB2 (0.37) | AVPR1BADRB1ADRB3DRD4MEN1 | |
| SCHEMBL10508328 | 0.81 | MOGAT2 (0.44) | CHRM3MEN1KMT2A | |
| SCHEMBL9770835 | 0.80 | SLC2A1 (0.35) | AVPR1BADRB1ADRB3DRD4MEN1 | |
| SCHEMBL9770964 | 0.79 | SLC5A2 (0.35) | AVPR1BDRD4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9770885 | 0.78 | HRH3 (0.35) | DRD4MEN1KMT2AHRH3 | |
| SCHEMBL9770815 | 0.78 | HRH3 (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |