Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884920 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL22017474 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL28375087 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL10924435 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL1199993 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL5407192 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL5409487 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL10995813 | 0.82 | ABCB1 (0.41) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL10508364 | 0.81 | ABCB1 (0.40) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 | |
| SCHEMBL9076894 | 0.81 | ABCB1 (0.40) | SMN1; SMN2ABCB1PI4KBLMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168025-B1 | PROCESS FOR PRODUCING AMINOTHIAZOLYLPROPENDICARBOXYLIC ACID MONOESTERS | SHIONOGI & CO., LTD. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4652652-A | PENICILLIN OR CEPHALOSPORIN INTERMEDIATE | SHIONOGI & CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0168025-A1 | Process for producing aminothiazolylpropendicarboxylic acid monoesters | SHIONOGI & CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |