Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505216 | 0.83 | CYP1A2 (0.39) | CA1CA2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10505480 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL4899037 | 0.81 | CCR2 (0.44) | ABCB1PI4KBCA1CA2SMN1; SMN2 | |
| SCHEMBL10508353 | 0.81 | SMN1; SMN2 (0.47) | ABCB1PI4KBCA1CA2SMN1; SMN2 | |
| SCHEMBL10504410 | 0.80 | SMN1; SMN2 (0.36) | CA1CA2SMN1; SMN2CCR2LMNA | |
| SCHEMBL10506393 | 0.78 | MAPT (0.39) | SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL28334812 | 0.77 | PI4KB (0.42) | PI4KBCA1CA2CCR2PTPRB | |
| SCHEMBL16748763 | 0.76 | PI4KB (0.44) | ABCB1PI4KBCA1CA2CCR2 | |
| SCHEMBL11186219 | 0.76 | PI4KB (0.37) | ABCB1PI4KBCA1CA2SMN1; SMN2 | |
| SCHEMBL11204633 | 0.76 | PI4KB (0.42) | PI4KBCA1CA2CCR2PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168025-B1 | PROCESS FOR PRODUCING AMINOTHIAZOLYLPROPENDICARBOXYLIC ACID MONOESTERS | SHIONOGI & CO., LTD. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4652652-A | PENICILLIN OR CEPHALOSPORIN INTERMEDIATE | SHIONOGI & CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0168025-A1 | Process for producing aminothiazolylpropendicarboxylic acid monoesters | SHIONOGI & CO., LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |