Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 17/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | PTGES | O14684 | 7/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252820 | 0.87 | PTGES2 (1.00) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL29503039 | 0.87 | PTGES2 (1.00) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL10509487 | 0.85 | PTGES2 (0.64) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL10510953 | 0.84 | PTGES2 (0.69) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL12675694 | 0.84 | PTGES2 (0.77) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL10508813 | 0.83 | PTGES2 (0.73) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL9738717 | 0.82 | PTGES2 (0.79) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL10510186 | 0.81 | PTGES2 (0.64) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL9737527 | 0.80 | PTGES2 (0.66) | PTGES2KDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL9737953 | 0.80 | PTGES2 (0.82) | PTGES2KDM4ECYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166591-B1 | INDOLE-2-ALKANOIC ACIDS AND THEIR USE AS PROSTAGLANDIN ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1989-11-23 | — | — | EP | claimed |
| EP-0166591-B1 | INDOLE-2-ALKANOIC ACIDS AND THEIR USE AS PROSTAGLANDIN ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1989-11-23 | — | — | EP | disclosed |