Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.77 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.77 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153666 | 1.00 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL9006725 | 1.00 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL11174788 | 1.00 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL7153662 | 1.00 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL11172401 | 1.00 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL29389524 | 0.90 | ADRB1 (0.64) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL10776036 | 0.90 | ADRB3 (0.73) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL7143110 | 0.89 | ADRB1 (0.95) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL9006683 | 0.89 | ADRB1 (0.95) | ADRB3ADRB1ADRB2CASP3CASP6 | |
| SCHEMBL7143114 | 0.89 | ADRB1 (0.95) | ADRB3ADRB1ADRB2CASP3CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803293-A | Tertiary amines | BEECHAM GROUP PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| EP-0142102-B1 | TERTIARY AMINES | BEECHAM GROUP PLC (GB) | 1987-09-23 | — | — | EP | disclosed |
| US-4593023-A | Antiobesity, hypoglycemic agent | BEECHAM GROUP P.L.C. (GB) | 1986-06-03 | — | — | US | disclosed |