Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | ACACA | Q13085 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23417044 | 0.95 | TSHR (0.55) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL23417047 | 0.88 | TSHR (0.48) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL13423702 | 0.88 | KDM4E (0.48) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL10506240 | 0.87 | TSHR (0.62) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL10506509 | 0.85 | TSHR (0.60) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL183822 | 0.85 | TSHR (0.51) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL10508196 | 0.84 | TSHR (0.55) | TSHRALDH1A1TDP1SMN1; SMN2EPHX2 | |
| SCHEMBL10972557 | 0.84 | TSHR (0.58) | TSHRALDH1A1TDP1SMN1; SMN2EPHX2 | |
| SCHEMBL28312829 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1SMN1; SMN2EPHX2 | |
| SCHEMBL28313658 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155810-B1 | N-(OMEGA-GLYCIDOXYALKYL)-SUBSTITUTED AMIDE COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0155810-A2 | N-(omega-glycidoxyalkyl)-substituted amide compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-25 | — | — | EP | disclosed |