Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493482 | 0.90 | NT5E (0.55) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL2709353 | 0.90 | NT5E (0.68) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL31327779 | 0.90 | NT5E (0.68) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL9493468 | 0.83 | NT5E (0.64) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL14690650 | 0.83 | NT5E (0.50) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL5101813 | 0.80 | LMNA (0.62) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL10505012 | 0.80 | LMNA (0.62) | NT5EKDM4ELMNA | |
| SCHEMBL9492496 | 0.79 | NT5E (0.50) | NT5ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL9493259 | 0.77 | C1R (0.50) | NT5EDHODHBACE1KDM4ELMNA | |
| SCHEMBL3826784 | 0.76 | NT5E (0.54) | NT5EBACE1KDM4EEPHX2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111329-B1 | FLUOROMETHYL QUINOLINE DERIVATIVES AND THEIR PREPARATION | ALKALOIDA VEGYESZETI GYAR (HU) | 1989-03-15 | — | — | EP | disclosed |