Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508734 | 1.00 | RAB9A (0.46) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL17888208 | 0.92 | TDP1 (0.52) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL17297790 | 0.86 | SMN1; SMN2 (0.46) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL17297961 | 0.86 | SMN1; SMN2 (0.46) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL13744480 | 0.86 | SMN1; SMN2 (0.46) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL17376555 | 0.86 | TSHR (0.51) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL19477704 | 0.85 | TDP1 (0.45) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL19195010 | 0.85 | TDP1 (0.45) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL3122498 | 0.84 | TSHR (0.50) | RAB9ATDP1MAPTSMN1; SMN2LIN28A | |
| SCHEMBL19102403 | 0.84 | TDP1 (0.44) | RAB9ATDP1MAPTSMN1; SMN2LIN28A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156191-B1 | CONDENSED DIAZEPINONES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0156191-A2 | Condensed diazepinones, process for their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-10-02 | — | — | EP | disclosed |