Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507289 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8555908 | 0.83 | MAPK1 (0.51) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10506918 | 0.81 | CDK1 (0.48) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7471060 | 0.79 | KDM4E (0.52) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4374748 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10956634 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL22620609 | 0.75 | KDM4E (0.51) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL913891 | 0.75 | KDM4E (0.56) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL22620607 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4376277 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150966-B1 | BENZOPYRAN DERIVATIVES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | FISONS plc (GB) | 1989-07-12 | — | — | EP | disclosed |
| US-4698345-A | Quinoline derivatives and their use as anti-asthmatic agents | FISONS PLC (GB) | 1987-10-06 | — | — | US | disclosed |
| EP-0150966-A2 | Benzopyran derivatives, compositions containing them and processes for their preparation | FISONS plc (GB) | 1985-08-07 | — | — | EP | disclosed |