Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508892 | 0.94 | TSHR (0.47) | TSHRMEN1KMT2ARAB9AHCRTR1 | |
| SCHEMBL10507883 | 0.91 | TSHR (0.40) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10507554 | 0.91 | TSHR (0.40) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10510137 | 0.90 | HPGD (0.46) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10506261 | 0.87 | TSHR (0.45) | TSHRNPC1RAB9AHCRTR1HPGD | |
| SCHEMBL10507470 | 0.83 | HCRTR1 (0.56) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10506333 | 0.83 | HPGD (0.44) | TSHRNPC1RAB9AHCRTR1HPGD | |
| SCHEMBL10508733 | 0.82 | ALDH1A1 (0.44) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10509426 | 0.81 | TSHR (0.50) | TSHRKMT2AHCRTR1HPGDALDH1A1 | |
| SCHEMBL10510261 | 0.81 | TSHR (0.53) | TSHRRAB9AHCRTR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155810-B1 | N-(OMEGA-GLYCIDOXYALKYL)-SUBSTITUTED AMIDE COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0155810-A2 | N-(omega-glycidoxyalkyl)-substituted amide compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-25 | — | — | EP | disclosed |