Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509164 | 1.00 | NPC1 (0.61) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL10664146 | 0.92 | NPC1 (0.73) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL7323266 | 0.92 | NPC1 (0.73) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL10667403 | 0.91 | NPC1 (0.67) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL10667407 | 0.91 | NPC1 (0.67) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL10508873 | 0.89 | NPC1 (0.66) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL11078570 | 0.89 | NPC1 (0.66) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL7284566 | 0.87 | NPC1 (0.63) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL15473519 | 0.85 | FFAR1 (0.55) | NPC1MEN1KMT2ARAB9ACHRM2 | |
| SCHEMBL15473538 | 0.85 | FFAR1 (0.55) | NPC1MEN1KMT2ARAB9ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172458-B1 | NOVEL BIOLOGICALLY ACTIVE COMPOUND HAVING ANTI-PROLYL ENDOPEPTIDASE ACTIVITY | SUNTORY LIMITED (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4743616-A | ANTIAMNESIA AGENTS | SUNTORY LIMITED (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0172458-A2 | Novel biologically active compound having anti-prolyl endopeptidase activity | SUNTORY LIMITED (JP) | 1986-02-26 | — | — | EP | disclosed |