SCHEMBL105095

SCHEMBL105095

c1ccc(-c2nc3ccccc3[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 1.00
RAB9A P51151 8/20 1.00
GAA P10253 2/20 1.00
KDM4E B2RXH2 13/20 0.75
ALDH1A1 P00352 12/20 0.75
SMN1; SMN2 Q16637 9/20 0.75
HSD17B10 Q99714 7/20 0.75
TP53 P04637 5/20 0.75
PKM P14618 2/20 0.75
PKN1 Q16512 1/20 0.75
PKN2 Q16513 1/20 0.75
ABCB11 O95342 1/20 0.75
NPSR1 Q6W5P4 1/20 0.75
HPGD P15428 10/20 0.72
MAPT P10636 5/20 0.72
GFER P55789 2/20 0.72
POLB P06746 1/20 0.72
LDHA P00338 1/20 0.68
EPHX2 P34913 1/20 0.68
KMT2A Q03164 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28005151 1.00 NPC1 (1.00) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL16416275 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
Hydrogen Sulfide SCHEMBL28075074 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
Potassium SCHEMBL4891434 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2147022 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL467859 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL4775610 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL27926515 0.98 NPC1 (0.96) NPC1RAB9AGAAKDM4EALDH1A1
SCHEMBL2252555 0.96 NPC1 (0.92) NPC1RAB9AGAAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL2147086 0.96 NPC1 (0.92) NPC1RAB9AGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11829 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080080-A Binuclear iridium metal conjugate, water-soluble nanoparticle, preparation method and application thereof in ultrasonic thrombolysis 2026-05-26 CN claimed
CN-122008677-A High-wear-resistance veneer and preparation process thereof 山东东宇鸿翔柜橱材料有限公司 2026-05-12 CN claimed
EP-4727657-A1 COSMETIC PREPARATION CONTAINING XANTHAN GUM, TERPINENES AND TERPINEOL Beiersdorf AG (DE) 2026-04-22 EP claimed
EP-4727519-A1 COSMETIC PREPARATION CONTAINING XANTHAN GUM AND VANILLIN DERIVATIVES Beiersdorf AG (DE) 2026-04-22 EP claimed
EP-4727521-A1 COSMETIC PREPARATION CONTAINING XANTHAN GUM AND ACETATES Beiersdorf AG (DE) 2026-04-22 EP claimed
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2026-03-26 US claimed
EP-4279532-B1 CROSSLINKED POLYGLYCEROL PARTIAL ESTERS EVONIK OPERATIONS GMBH (DE) 2026-03-25 EP claimed
EP-4157213-B1 SUNSCREEN WITH A COMBINATION OF CARNAUBA WAX AND HYDROGENATED RAPESEED OIL BEIERSDORF AG (DE) 2026-03-18 EP claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
EP-4687819-A1 SUNSCREEN CONTAINING TEREPHTHALYLIDENE DICAMPHOR SULFONIC ACID AND GLYCOLS Beiersdorf AG (DE) 2026-02-11 EP claimed
US-5017686-A Production of aromatic polyamide using a fused ring stabilizer HUELS AKTIENGESELLSCHAFT (DE) 1991-05-21 US claimed
EP-0216084-B1 IMPROVED SUNSCREEN AND MOISTURIZER Richardson-Vicks, Inc. (US) 1991-01-23 EP claimed
US-4895727-A Using water soluble zinc compound CHEMEX PHARMACEUTICALS, INC. (US) 1990-01-23 US claimed
EP-0154303-B1 LIGHT AND SUN SCREEN AGENTS Beiersdorf Aktiengesellschaft (DE) 1989-04-26 EP claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4607071-A Process for spin-dyeing of acid-modified polymers of copolymers of acrylonitrile using rapid-fixing di-quaternary cationic dyes HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-19 US claimed
EP-0001246-A1 Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles CASSELLA Aktiengesellschaft (DE) 1979-04-04 EP claimed
US-4082767-A CATALYTIC HYDROLYSIS OF HYDANTOIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-04 US claimed
US-4057425-A SILVER HALIDE EMULSION POLAROID CORPORATION (US) 1977-11-08 US claimed
US-4001268-A SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1977-01-04 US claimed