Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709374 | 1.00 | CTSK (0.57) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL27709512 | 0.98 | CTSK (0.55) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL28779415 | 0.85 | CTSK (0.45) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL3524258 | 0.83 | CTSK (0.59) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL12203697 | 0.83 | CTSK (0.59) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL27689689 | 0.83 | CTSK (0.44) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL10656689 | 0.82 | CTSK (0.65) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL6447508 | 0.81 | CTSK (0.54) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL6447502 | 0.81 | CTSK (0.54) | CTSKCTSSEPHX1HDAC4HDAC1 | |
| SCHEMBL1424703 | 0.81 | CTSK (0.56) | CTSKCTSSEPHX1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372653-A | Diphenyl methanol derivative, preparation method thereof and application of diphenyl methanol derivative in medicine | JIANGSU HENGRUI MEDICINE CO | 2012-03-14 | — | — | CN | disclosed |
| EP-0310918-A2 | Peptide-like amino-acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | disclosed |