Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | PTAFR | P25105 | 19/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456051 | 0.92 | OPRK1 (0.64) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10870209 | 0.92 | OPRK1 (0.56) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10454946 | 0.92 | OPRK1 (0.68) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9542386 | 0.90 | OPRK1 (0.70) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9669397 | 0.90 | OPRK1 (0.70) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10508885 | 0.89 | OPRK1 (0.53) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9667521 | 0.88 | OPRK1 (0.68) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10455818 | 0.87 | OPRK1 (0.67) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL9421189 | 0.87 | PTAFR (0.72) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL10455817 | 0.86 | PTAFR (0.68) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194416-A1 | Thieno-triazolo-1,4-diazepino-2-carboxamides, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1986-09-17 | — | — | EP | claimed |
| EP-0194416-B1 | THIENO-TRIAZOLO-1,4-DIAZEPINO-2-CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | disclosed |