Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 11/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512325 | 1.00 | KMT2A (0.48) | KMT2AL3MBTL1ACELMNAACE2 | |
| SCHEMBL10511237 | 0.93 | CMA1 (0.45) | KMT2AACELMNAACE2CMA1 | |
| SCHEMBL10511252 | 0.93 | CMA1 (0.45) | KMT2AACELMNAACE2CMA1 | |
| SCHEMBL8331221 | 0.83 | ACE (0.60) | KMT2AL3MBTL1ACELMNAACE2 | |
| SCHEMBL20484652 | 0.83 | ACE (0.60) | KMT2AL3MBTL1ACELMNAACE2 | |
| SCHEMBL8331218 | 0.83 | ACE (0.60) | KMT2AL3MBTL1ACELMNAACE2 | |
| SCHEMBL7274015 | 0.83 | ACE (0.60) | KMT2AL3MBTL1ACELMNAACE2 | |
| SCHEMBL5206341 | 0.83 | PIN1 (0.38) | KMT2ALMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22804056 | 0.82 | CYP2C9 (0.47) | KMT2AACELMNAACE2CYP3A4 | |
| SCHEMBL30122483 | 0.82 | CYP2C9 (0.47) | KMT2AACELMNAACE2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205209-B1 | DECAPEPTIDES HAVING HYPOTENSIVE ACTION AND PROCESS FOR THEIR PREPARATION | ENIRICERCHE S.p.A. (IT) | 1989-11-29 | — | — | EP | disclosed |
| US-4810779-A | Decapeptides having hypotensive action and process for their preparation | ENICHEM ELASTOMERI S.P.A. (IT) | 1989-03-07 | — | — | US | disclosed |
| EP-0205209-A2 | Decapeptides having hypotensive action and process for their preparation | ENIRICERCHE S.p.A. (IT) | 1986-12-17 | — | — | EP | disclosed |