Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 8/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510198 | 0.99 | HSD17B10 (0.49) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9511463 | 0.99 | HSD17B10 (0.49) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9509291 | 0.98 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9511483 | 0.98 | TSHR (0.44) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9510178 | 0.96 | HSD17B10 (0.49) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9511406 | 0.96 | HSD17B10 (0.49) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9508818 | 0.96 | HSD17B10 (0.45) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9509482 | 0.96 | HSD17B10 (0.45) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9512402 | 0.96 | HSD17B10 (0.45) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL9512279 | 0.96 | HSD17B10 (0.42) | HSD17B10TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |