Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863231 | 0.96 | POLB (0.41) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10928728 | 0.87 | PIK3CD (0.40) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10875591 | 0.87 | PIK3CD (0.40) | POLBALDH1A1LMNAMAPTPIK3CG | |
| SCHEMBL10756839 | 0.86 | KDM4E (0.40) | ALDH1A1LMNAMAPTPIK3CGPIK3CD | |
| SCHEMBL10513589 | 0.85 | PIK3CG (0.51) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10923513 | 0.85 | PIK3CD (0.40) | POLBALDH1A1LMNAMAPTPIK3CG | |
| SCHEMBL10882386 | 0.84 | PIK3CD (0.38) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10876818 | 0.83 | PIK3CD (0.41) | ALDH1A1LMNAMAPTPIK3CGPIK3CD | |
| SCHEMBL6240583 | 0.82 | ALDH1A1 (0.47) | POLBALDH1A1LMNAMAPTPIK3CG | |
| SCHEMBL10929947 | 0.82 | KDM4E (0.39) | ALDH1A1LMNAMAPTPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332033-A2 | N-cyclopropyl anilines and their use in processes for the synthesis of 1-cyclopropyl-quinolone-carboxylic acids and their derivatives | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0230274-A2 | Derivatives of 7-(azabicycloalkyl)-quinoloncarboxylic acid and -naphthyridoncarboxylic acid | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |
| EP-0117473-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0117474-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0121727-B1 | BACTERICIDAL AGENT BASED ON QUINOLONECARBOXYLIC ACIDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0113091-B1 | MICROBIOCIDAL AGENTS BASED ON QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0118854-B1 | BACTERICIDAL AGENT CONTAINING QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0121727-A1 | Bactericidal agent based on quinolonecarboxylic acids | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0118854-A1 | Bactericidal agent containing quinolone-carboxylic acids | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0117473-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0113091-A1 | Microbiocidal agents based on quinolone-carboxylic acids | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |