Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512781 | 0.89 | HPGD (0.47) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10513492 | 0.83 | KDM4E (0.65) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10513726 | 0.83 | KDM4E (0.54) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL20821410 | 0.77 | KDM4E (0.55) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10041659 | 0.77 | KDM4E (0.51) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10041662 | 0.77 | HPGD (0.49) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10041700 | 0.77 | HPGD (0.49) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10513759 | 0.75 | MAPT (0.51) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL14644210 | 0.74 | KDM4E (0.49) | HPGDKDM4EMAPTPOLBLMNA | |
| SCHEMBL10041698 | 0.74 | ALDH1A1 (0.49) | HPGDKDM4EMAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331093-A1 | Benzimidazo[1,2-c]quinazolines, their preparation and use | KNOLL AG (DE) | 1989-09-06 | — | — | EP | disclosed |