Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514158 | 0.88 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDACHE | |
| SCHEMBL10514155 | 0.88 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDACHE | |
| SCHEMBL10514540 | 0.82 | HDAC3 (0.39) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL10514674 | 0.73 | CLK1 (0.44) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL10515962 | 0.70 | HDAC3 (0.54) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL10514536 | 0.69 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10514534 | 0.69 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10512914 | 0.69 | MEN1 (0.52) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9238352 | 0.69 | CLK1 (0.54) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9573691 | 0.68 | PIM1 (0.52) | IGF1RPIM1PIM2HPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299620-A1 | Thiazolidinedione derivatives | BEECHAM GROUP PLC (GB) | 1989-01-18 | — | — | EP | disclosed |