Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 10/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514534 | 1.00 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10514540 | 0.88 | HDAC3 (0.39) | IGF1RHPGDCYP3A4ESRRATDP1 | |
| SCHEMBL10515952 | 0.85 | HDAC4 (0.54) | PIM1PIM2HPGDAKR1B1MEN1 | |
| SCHEMBL10515957 | 0.85 | HDAC4 (0.54) | PIM1PIM2HPGDAKR1B1MEN1 | |
| SCHEMBL10514663 | 0.85 | PIM1 (0.59) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10514668 | 0.85 | PIM1 (0.59) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10514158 | 0.82 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10514155 | 0.82 | IGF1R (0.49) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10513810 | 0.81 | IGF1R (0.48) | IGF1RPIM1PIM2HPGDAKR1B1 | |
| SCHEMBL10513814 | 0.81 | IGF1R (0.48) | IGF1RPIM1PIM2HPGDAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299620-A1 | Thiazolidinedione derivatives | BEECHAM GROUP PLC (GB) | 1989-01-18 | — | — | EP | claimed |
| EP-0299620-A1 | Thiazolidinedione derivatives | BEECHAM GROUP PLC (GB) | 1989-01-18 | — | — | EP | disclosed |