SCHEMBL10515698

SCHEMBL10515698

CC(C)(C)CC(C)(C)c1ccc(-c2ccc(C(C)(C)CC(C)(C)C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.67
CYP3A4 P08684 5/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
HIF1A Q16665 3/20 0.41
CYP2D6 P10635 2/20 0.41
KIF11 P52732 4/20 0.39
CNR2 P34972 1/20 0.39
MDH1 P40925 3/20 0.37
MDH2 P40926 3/20 0.37
ESR1 P03372 3/20 0.37
ESR2 Q92731 1/20 0.37
MEN1 O00255 3/20 0.37
USP2 O75604 3/20 0.37
TP53 P04637 3/20 0.37
MAPT P10636 3/20 0.37
SLC6A2 P23975 3/20 0.37
SLC6A4 P31645 3/20 0.37
SLC6A3 Q01959 3/20 0.37
KMT2A Q03164 3/20 0.37
KCNH2 Q12809 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647964 0.89 SHBG (0.88) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL24227113 0.82 SHBG (0.48) SHBGCYP3A4SMN1; SMN2KIF11MDH1
SCHEMBL8768818 0.82 SHBG (0.64) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL18286393 0.81 SHBG (0.47) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL14848456 0.81 SHBG (0.47) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL14825135 0.81 SHBG (0.47) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL17132080 0.81 SHBG (0.47) SHBGCYP3A4SMN1; SMN2KIF11CNR2
SCHEMBL8798776 0.80 SHBG (0.61) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL13591329 0.80 SHBG (0.61) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
SCHEMBL21138351 0.80 SHBG (0.68) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11041027-B2 Polymerization process for producing ethylene based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2021-06-22 US disclosed
US-10870713-B2 Procatalyst and polymerization process using the same DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-22 US disclosed
EP-3736299-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS Dow Global Technologies Llc (US) 2020-11-11 EP disclosed
EP-3317312-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-10 EP disclosed
EP-3356431-B1 PROCATALYST AND POLYMERIZATION PROCESS USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-04-22 EP disclosed
US-10597473-B2 Polymerization process for producing ethylene based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-24 US disclosed
EP-3317313-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-19 EP disclosed
US-20180265604-A1 PROCATALYST AND POLYMERIZATION PROCESS USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-20 US disclosed
US-20180194871-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-12 US disclosed
US-20180186910-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-05 US disclosed
EP-0323403-A2 Lubricant composition CIBA-GEIGY AG (CH) 1989-07-05 EP disclosed