Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533766 | 0.79 | CYP3A4 (0.52) | MAOBMAOACYP19A1CYP3A4MAPT | |
| SCHEMBL20117722 | 0.78 | DAO (0.53) | — | |
| SCHEMBL28173296 | 0.78 | DAO (0.53) | — | |
| SCHEMBL49433 | 0.77 | MAOB (0.62) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL30583096 | 0.77 | MAOB (0.62) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL1108477 | 0.76 | TAAR1 (0.50) | MAOASMN1; SMN2HRH3 | |
| SCHEMBL9719335 | 0.75 | MAOB (0.60) | MAOBMAOACYP19A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL8644377 | 0.75 | MAOB (0.64) | MAOBMAOACYP19A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL10936113 | 0.75 | MAOB (0.64) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL28814222 | 0.75 | IDH1 (0.46) | MAOBMAOAPARP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329169-A1 | N-(lower alkyl)-2-(3'-ureidobenzyl)-pyrrolidines | SYNTEX (U.S.A.) INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4826869-A | GLAUCOMA | SYNTEX (U.S.A.) INC. (US) | 1989-05-02 | — | — | US | disclosed |