Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957839 | 0.85 | MAOA (0.40) | DAOACHE | |
| SCHEMBL23528212 | 0.79 | DAO (0.44) | DAOTAAR1IDO1 | |
| SCHEMBL10516151 | 0.78 | MAOB (0.46) | — | |
| SCHEMBL23528205 | 0.77 | CHRM2 (0.50) | DAOTAAR1IDO1KDM5B | |
| SCHEMBL1263547 | 0.77 | TAAR1 (0.60) | DAOTAAR1IDO1ACHE | |
| SCHEMBL30000562 | 0.77 | TAAR1 (0.60) | DAOTAAR1IDO1ACHE | |
| SCHEMBL29459538 | 0.77 | TAAR1 (0.60) | DAOTAAR1IDO1ACHE | |
| SCHEMBL1108477 | 0.76 | TAAR1 (0.50) | DAOTAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL27287864 | 0.74 | TAAR1 (0.48) | DAOTAAR1KMT2A | |
| SCHEMBL6704635 | 0.74 | HRH3 (0.61) | DAOMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207482-A | Pyrimidine derivatives for treating cancer | 默克专利股份公司 | 2017-09-26 | — | — | CN | claimed |
| CN-107207482-A | Pyrimidine derivatives for treating cancer | 默克专利股份公司 | 2017-09-26 | — | — | CN | disclosed |