Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 12/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10514077 | 1.00 | NOD1 (0.59) | NOD1KMT2AGLP1RLPAR3SLC6A5 | |
| SCHEMBL18796593 | 0.97 | NOD1 (0.59) | NOD1KMT2ALPAR3 | |
| SCHEMBL18796573 | 0.97 | NOD1 (0.59) | NOD1KMT2ALPAR3 | |
| SCHEMBL18796584 | 0.97 | NOD1 (0.59) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL18796601 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL10517315 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL10332244 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL10332245 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL10517288 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 | |
| Hydrochloric Acid SCHEMBL18796561 | 0.95 | NOD1 (0.58) | NOD1KMT2ALPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320976-A1 | Arginine derivatives and cosmetic compositions comprising the same | AJINOMOTO CO., INC. (JP) | 1989-06-21 | — | — | EP | disclosed |