Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722149 | 0.87 | CYSLTR2 (0.60) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL7094939 | 0.79 | AR (0.71) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL10518806 | 0.79 | CYSLTR2 (0.45) | DRD2DRD4DRD3RAB9ANPC1 | |
| SCHEMBL10516657 | 0.79 | MAPT (0.48) | DRD2DRD4DRD3MAPTTP53 | |
| SCHEMBL10520042 | 0.78 | PPARA (0.56) | MAPTTP53PPARA | |
| SCHEMBL10519163 | 0.78 | TP53 (0.49) | DRD2DRD4DRD3RAB9ASMN1; SMN2 | |
| SCHEMBL10517008 | 0.78 | MAOB (0.57) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL10516316 | 0.77 | CYSLTR2 (0.43) | DRD2DRD4DRD3SMN1; SMN2MAPT | |
| SCHEMBL10515339 | 0.76 | CYSLTR2 (0.47) | DRD2DRD4DRD3CYSLTR2CYSLTR1 | |
| SCHEMBL10519902 | 0.76 | PPARA (0.58) | MAPTTP53CYSLTR2CYSLTR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310370-A1 | 2-aryl substituted heterocyclic compounds as antiallgeric and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |