Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516601 | 0.87 | DRD2 (0.52) | CYSLTR2CYSLTR1HDAC1HDAC6MAPT | |
| SCHEMBL9721984 | 0.86 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1MAPTTP53PPARA | |
| SCHEMBL9722077 | 0.81 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTPS1PPARAPPARG | |
| SCHEMBL9722007 | 0.81 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1MAPTTP53PPARA | |
| SCHEMBL9722119 | 0.80 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTTP53CTPS1 | |
| SCHEMBL9721963 | 0.80 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MAPTTP53CTPS1 | |
| SCHEMBL9721919 | 0.80 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MAPTTP53PPARA | |
| SCHEMBL9721973 | 0.79 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1CTPS1PPARAPPARG | |
| SCHEMBL9721986 | 0.79 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MAPTTP53PPARA | |
| SCHEMBL9721936 | 0.77 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1MAPTCTPS1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310370-A1 | 2-aryl substituted heterocyclic compounds as antiallgeric and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | claimed |
| US-5103014-A | Antiinflammatory or/and antiallergic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |
| US-4942236-A | ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |
| US-4895953-A | 2-Aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |