Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10515247 | 0.99 | ACMSD (0.40) | ACMSDHNF4AMCL1DHFRSLC6A2 | |
| SCHEMBL10515291 | 0.85 | CSNK2A1 (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6GRIK1 | |
| SCHEMBL10514170 | 0.84 | SLC6A2 (0.51) | SLC6A2SLC6A4KCNH2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10517902 | 0.84 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3CYP2D6GRIK1 | |
| SCHEMBL10513058 | 0.82 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10514179 | 0.81 | SLC6A2 (0.45) | SLC6A2SLC6A4KCNH2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10516728 | 0.80 | SLC6A2 (0.37) | SLC6A2SLC6A4KCNH2SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10516135 | 0.79 | SLC6A2 (0.39) | SLC6A2SLC6A4KCNH2SLC6A3CYP2D6 | |
| SCHEMBL10515316 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10517186 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299663-A2 | Antihistaminic aromatic tetrahydroazepinones (and thiones) | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |