Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Phenylethylidene Hydrazine SCHEMBL1005101 | 1.00 | MAOB (0.52) | MAOBLOXL2IDO1NOS3NOS1 | |
| SCHEMBL25271061 | 0.79 | MAOB (0.57) | MAOBLOXL2IDO1NOS3NOS1 | |
| SCHEMBL4037964 | 0.79 | MAOB (0.57) | MAOBLOXL2IDO1NOS3NOS1 | |
| SCHEMBL5284766 | 0.76 | LOXL2 (0.46) | LOXL2CA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15117847 | 0.76 | LOXL2 (0.46) | MAOBLOXL2IDO1TAAR1ALDH1A1 | |
| SCHEMBL22380794 | 0.76 | SMN1; SMN2 (0.46) | MAOBLOXL2IDO1CYP2A6HTR2A | |
| SCHEMBL10805702 | 0.76 | LOXL2 (0.46) | LOXL2CA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2683051 | 0.76 | SMN1; SMN2 (0.46) | MAOBLOXL2IDO1CYP2A6HTR2A | |
| SCHEMBL1060278 | 0.75 | MAOB (0.59) | MAOBIDO1NOS3NOS1NOS2 | |
| SCHEMBL15702910 | 0.75 | MAOB (0.52) | MAOBLOXL2IDO1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114453-A1 | PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME | Neurawell Therapeutics (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022165382-A1 | PHENYLETHYLIDENEHYDRAZINE COMBINATION THERAPIES | Neurawell Therapeutics (US) | 2022-08-04 | — | — | WO | disclosed |
| EP-2846804-B1 | TETRAHYDRONAPHTHYRIDINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2846794-B1 | BICYCLIC SULFONE COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9023564-B2 | Azoquinone compound, electrophotographic photoconductor, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-9023564-B2 | Azoquinone compound, electrophotographic photoconductor, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-20140295335-A1 | AZOQUINONE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140295335-A1 | AZOQUINONE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-8501995-B2 | β-phenylethylidenehydrazine derivatives | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-08-06 | — | — | US | disclosed |
| US-8501995-B2 | β-phenylethylidenehydrazine derivatives | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-08-06 | — | — | US | disclosed |
| US-8501995-B2 | β-phenylethylidenehydrazine derivatives | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-08-06 | — | — | US | disclosed |
| US-20110009492-A1 | ß-PHENYLETHYLIDENEHYDRAZINE DERIVATIVES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-01-13 | — | — | US | disclosed |
| US-20110009492-A1 | ß-PHENYLETHYLIDENEHYDRAZINE DERIVATIVES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009492-A1 | ß-PHENYLETHYLIDENEHYDRAZINE DERIVATIVES | CYP3A5, TPSD1, CYP3A4 | MAOB 75/4885LOXL2 4261/4885IDO1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.