Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GNRHR | P30968 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518487 | 0.90 | HPGD (0.54) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10517997 | 0.90 | ALDH1A1 (0.57) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10518529 | 0.90 | HPGD (0.57) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10516662 | 0.89 | KDM4E (0.56) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10517677 | 0.88 | KMT2A (0.57) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10520576 | 0.88 | HPGD (0.62) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10727441 | 0.86 | ALDH1A1 (0.58) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10517598 | 0.86 | HPGD (0.54) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10518082 | 0.86 | HPGD (0.54) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL10516685 | 0.86 | POLB (0.60) | HPGDHSD17B10KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184384-B1 | SUBSTITUTED DIHYDROQUINOLONE CARBOXYLIC ACIDS, ANTI-BACTERIAL COMPOSITIONS CONTAINING THEM | PFIZER INC. (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4623650-A | BACTERICIDES | PFIZER INC. (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0184384-A1 | Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them | PFIZER INC. (US) | 1986-06-11 | — | — | EP | disclosed |