Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524090 | 0.86 | PIK3CG (0.47) | PIK3CGALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10868877 | 0.80 | PIK3CG (0.63) | PIK3CGALDH1A1SMN1; SMN2NPC1HTT | |
| Hydrochloric Acid SCHEMBL10870013 | 0.79 | PIK3CG (0.61) | PIK3CGALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL10519095 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL10518084 | 0.70 | ALDH1A1 (0.68) | PIK3CGALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16434151 | 0.65 | ALDH1A1 (0.56) | PIK3CGALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11723023 | 0.62 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2RAB9AKDM4EKMT2A | |
| SCHEMBL4534987 | 0.62 | PIK3CG (1.00) | PIK3CGALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL10713902 | 0.62 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL16632865 | 0.61 | PIK3CG (0.45) | PIK3CGALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | claimed |