Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703118 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL10522142 | 0.80 | HTT (0.42) | NPSR1SMN1; SMN2MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL10518465 | 0.78 | NPSR1 (0.40) | NPSR1SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL1162993 | 0.73 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL10517840 | 0.72 | SMN1; SMN2 (0.36) | NPSR1SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL23661943 | 0.70 | APP (0.56) | NPSR1MEN1GAAKMT2ACYP19A1 | |
| SCHEMBL9503659 | 0.68 | CYP19A1 (0.58) | SMN1; SMN2CYP19A1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL16166404 | 0.67 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL6978954 | 0.67 | MEN1 (0.61) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL11831281 | 0.67 | TSHR (0.48) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843083-A | 2-pyridylacetic acid derivative, and pharmaceutical composition containing the same and method of treating a peptic ulcer | SUNTORY LIMITED (JP) | 1989-06-27 | — | — | US | disclosed |