Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADH5 | P11766 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828266 | 0.87 | MAOB (0.54) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL8828261 | 0.87 | MAOB (0.54) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL6852411 | 0.81 | ENPP2 (0.54) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL6852406 | 0.81 | ENPP2 (0.54) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL7385020 | 0.81 | MAOB (0.52) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL8401613 | 0.81 | MAOB (0.52) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL1238616 | 0.77 | ESR1 (0.67) | MAOBMAPTKDM4EMEN1MITF | |
| SCHEMBL1238620 | 0.77 | ESR1 (0.67) | MAOBMAPTKDM4EMEN1MITF | |
| Hydrochloric Acid SCHEMBL7328751 | 0.75 | ESR1 (0.65) | MAOBMAPTKDM4EMEN1MITF | |
| Hydrochloric Acid SCHEMBL7328757 | 0.75 | ESR1 (0.65) | MAOBMAPTKDM4EMEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |