Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 8/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799499 | 0.96 | GHSR (0.56) | GHSRBACE1GNPATMMP2 | |
| SCHEMBL30628702 | 0.93 | GHSR (0.56) | GHSRGNPATMMP2 | |
| SCHEMBL29531757 | 0.93 | GHSR (0.56) | GHSRGNPATMMP2 | |
| SCHEMBL29720348 | 0.91 | BACE1 (0.60) | GHSRBACE1CTSD | |
| SCHEMBL29575648 | 0.90 | NAALAD2 (0.56) | GHSRBACE1GNPATCTSD | |
| SCHEMBL30579779 | 0.90 | GNPAT (0.61) | GHSRGNPATMMP2 | |
| SCHEMBL30974110 | 0.90 | MME (0.55) | BACE1MMP2 | |
| SCHEMBL31254405 | 0.89 | GNPAT (0.62) | GHSRGNPATMMP2 | |
| SCHEMBL1711453 | 0.89 | GNPAT (0.62) | GHSRGNPATMMP2 | |
| SCHEMBL1711458 | 0.89 | GNPAT (0.62) | GHSRGNPATMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156540-B1 | A GLUTAMATE RECEPTOR INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4855405-A | Glutamate receptor inhibitor | TOKYO METROPOLITAN INSTITUTE FOR NEUROSCIENCES (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0156540-A1 | A glutamate receptor inhibitor | Takeda Chemical Industries, Ltd. (JP) | 1985-10-02 | — | — | EP | disclosed |