Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520529 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10519095 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9430279 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8648939 | 0.77 | HRH2 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10519089 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL10518071 | 0.77 | ALDH1A1 (0.97) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9298440 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10520818 | 0.76 | HPGD (0.48) | ALDH1A1MAPTKMT2AKDM4EHSD17B10 | |
| SCHEMBL10520966 | 0.75 | PIK3CG (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9297795 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-B1 | THIENYLTHIAZOLE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |