Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.79 |
| ▸ | TNF | P01375 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.79 |
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | PDE4A | P27815 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.79 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.79 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412111 | 0.99 | ADORA2B (0.81) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| 1-[4-Carboxypropyl]-3,7-Dimethylxanthine SCHEMBL5420399 | 0.95 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8686347 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8686071 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8696287 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8150960 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8687852 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9123561 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9123538 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8687521 | 0.90 | ADORA2B (0.97) | ADORA2BTNFLMNACYP1A2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198190-B1 | COMPOUNDS HAVING ANTIPLATELET AGGREGATION ACTIVITY, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELLEM INDUSTRIA FARMACEUTICA S.p.A. (IT) | 1989-05-31 | — | — | EP | disclosed |
| US-4737502-A | DIMETHYLXANTHINYL-SUBSTITUTED 4,5,6,7-TETRAHYDROTHIENO(3,2-C)P PYRIDINES | ELLEM INDUSTRIA FARMACEUTICA S.P.A. (IT) | 1988-04-12 | — | — | US | disclosed |
| EP-0199190-A2 | Separating element for separating solid particles, suspended in a gaseous current, by centrifugal force in a cylindrical whirl chamber | Anton Piller GmbH & Co. KG (DE) | 1986-10-29 | — | — | EP | disclosed |