Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505905 | 0.85 | KDM4E (0.53) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL799202 | 0.85 | KDM4E (0.53) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL14668870 | 0.84 | KDM4E (0.56) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL1535944 | 0.81 | KDM4E (0.53) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL1535946 | 0.80 | KDM4E (0.51) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL18380643 | 0.79 | KDM4E (0.61) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL29616919 | 0.79 | KDM4E (0.61) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL9702416 | 0.79 | KDM4E (0.50) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL1535976 | 0.79 | KDM4E (0.50) | KDM4EHTTATMALDH1A1HRH3 | |
| SCHEMBL4159068 | 0.77 | KDM4E (0.54) | KDM4EHTTATMALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824843-A | Substituted amide inhibitors of cholesterol absorption | WARNER-LAMBERT COMPANY (US) | 1989-04-25 | — | — | US | disclosed |