Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540 | 0.86 | KDM4E (0.50) | KDM4EATMALDH1A1HTT | |
| SCHEMBL29527964 | 0.86 | KDM4E (0.50) | KDM4EATMALDH1A1HTT | |
| SCHEMBL6299778 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1 | |
| SCHEMBL10737493 | 0.84 | KDM4E (0.47) | KDM4EATMALDH1A1HTT | |
| SCHEMBL7105642 | 0.82 | KDM4E (0.47) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL8491858 | 0.82 | KDM4E (0.47) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL7023321 | 0.81 | KDM4E (0.56) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL14668870 | 0.81 | KDM4E (0.56) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL11487649 | 0.81 | KDM4E (0.46) | KDM4EATMALDH1A1HTTHRH3 | |
| SCHEMBL22560182 | 0.80 | KDM4E (0.43) | KDM4EATMALDH1A1HTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496548-A1 | Carbacyclin analogs | PURDUE RESEARCH FOUNDATION (US) | 1992-07-29 | — | — | EP | disclosed |