Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522050 | 1.00 | ACE (0.46) | ACELMNASMN1; SMN2ALDH1A1ACE2 | |
| SCHEMBL10520233 | 0.93 | ACE (0.49) | ACELMNASMN1; SMN2ALDH1A1ABCB11 | |
| SCHEMBL10520228 | 0.93 | ACE (0.49) | ACELMNASMN1; SMN2ALDH1A1ABCB11 | |
| SCHEMBL10522606 | 0.90 | ACE (0.48) | ACELMNASMN1; SMN2ALDH1A1ACE2 | |
| SCHEMBL10522615 | 0.90 | ACE (0.48) | ACELMNASMN1; SMN2ALDH1A1ACE2 | |
| SCHEMBL10796436 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ALOX15 | |
| SCHEMBL10796078 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ALOX15 | |
| SCHEMBL10796062 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ALOX15 | |
| SCHEMBL10796279 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ALOX15 | |
| SCHEMBL10799042 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2ACE2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | claimed |
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | disclosed |