Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 0.44 |
| ▸ | F3 | P13726 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802354 | 1.00 | F7 (0.44) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL27875985 | 0.93 | F7 (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL27876083 | 0.91 | F7 (0.47) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802025 | 0.90 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802035 | 0.90 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802364 | 0.86 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802003 | 0.86 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9801998 | 0.86 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802374 | 0.86 | LIPG (0.49) | F7F3MMP2KDM4EMAPT | |
| SCHEMBL9802425 | 0.86 | F7 (0.47) | F7F3MMP2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808572-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4785004-A | ANTIALLERGENS, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0228045-A2 | Aromatic thioethers | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |