Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647312 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2CA12CA2CA9 | |
| SCHEMBL9625868 | 0.74 | LMNA (0.38) | GLP1RLMNASMN1; SMN2CA12CA2 | |
| SCHEMBL10514950 | 0.70 | LMNA (0.38) | GLP1RLMNASMN1; SMN2CA12CA2 | |
| SCHEMBL10123082 | 0.69 | LMNA (0.40) | GLP1RLMNASMN1; SMN2CA12CA2 | |
| SCHEMBL13647010 | 0.69 | LMNA (0.48) | LMNA | |
| SCHEMBL7753780 | 0.68 | LMNA (0.52) | LMNASMN1; SMN2CA12CA2CA9 | |
| SCHEMBL13024699 | 0.67 | LMNA (0.32) | LMNAALDH1A1 | |
| SCHEMBL6462055 | 0.67 | MEN1 (0.39) | ALDH1A1 | |
| SCHEMBL11440853 | 0.67 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL2179204 | 0.67 | PDE10A (0.35) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302311-A2 | Aryloxy (or thio)aminopyrimidines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |