Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 7/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523376 | 0.93 | ABCB11 (0.38) | ABCB11MEN1ALDH1A1KMT2A | |
| SCHEMBL10525202 | 0.88 | ABCB11 (0.38) | ABCB11MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL10525087 | 0.84 | KMT2A (0.39) | F3PTPN1MEN1KMT2ATDP1 | |
| SCHEMBL10524931 | 0.83 | TP53 (0.41) | F3ALDH1A1 | |
| SCHEMBL10524858 | 0.82 | ABCB11 (0.52) | ABCB11MEN1MAPK1KMT2ATDP1 | |
| SCHEMBL10524461 | 0.82 | KMT2A (0.36) | ALOX15ABCB11GSK3BP2RX7EPHX2 | |
| SCHEMBL10524465 | 0.80 | ABCB11 (0.40) | ALOX15ABCB11GSK3BP2RX7EPHX2 | |
| SCHEMBL10527255 | 0.80 | ABCB11 (0.38) | ABCB11MEN1KMT2A | |
| SCHEMBL10524179 | 0.78 | ABCB11 (0.37) | ABCB11MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL29370965 | 0.77 | ABCB11 (0.45) | ALOX15ABCB11EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840965-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1989-06-20 | — | — | US | disclosed |