Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRAT | P43155 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15576809 | 1.00 | CRAT (0.38) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL10936490 | 0.83 | CRAT (0.45) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL7731906 | 0.77 | CRAT (0.41) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL1144276 | 0.77 | CRAT (0.41) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL1144295 | 0.77 | CRAT (0.41) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL23116550 | 0.76 | ALDH1A1 (0.47) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL23116551 | 0.76 | ALDH1A1 (0.47) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL3692105 | 0.75 | CA1 (0.41) | KMT2A | |
| SCHEMBL11198123 | 0.75 | CRAT (0.40) | CRATKDM4EMAPTTHRBALOX15 | |
| SCHEMBL10940119 | 0.75 | GABRR1 (0.43) | CRATKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177574-B1 | AMINOCARNITINES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1989-12-20 | — | — | EP | claimed |
| US-4781863-A | FROM 6-CHLOROMETHYLURACIL | CORNELL RESEARCH FOUNDATION, INC. (US) | 1988-11-01 | — | — | US | claimed |
| US-8673946-B2 | 4-trimethylammonio-butyrates as CPT2 inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2014-03-18 | — | — | US | disclosed |
| EP-0177574-B1 | AMINOCARNITINES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1989-12-20 | — | — | EP | disclosed |