Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522890 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10522385 | 0.99 | CYP2C9 (0.45) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10522377 | 0.99 | CYP2C9 (0.45) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10522730 | 0.91 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10522718 | 0.91 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10384069 | 0.89 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10385073 | 0.89 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10385072 | 0.89 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10383373 | 0.88 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL10521324 | 0.84 | METAP2 (0.40) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | disclosed |