⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13305742 | 0.76 | — | — | |
| SCHEMBL12284090 | 0.68 | — | — | |
| SCHEMBL13564518 | 0.65 | — | — | |
| SCHEMBL2460286 | 0.64 | TSHR (0.38) | — | |
| SCHEMBL31145201 | 0.64 | — | — | |
| SCHEMBL2038774 | 0.63 | — | — | |
| SCHEMBL9976679 | 0.62 | — | — | |
| SCHEMBL565535 | 0.59 | NOS3 (0.35) | — | |
| SCHEMBL5029860 | 0.58 | — | — | |
| SCHEMBL19716089 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707795-A | Preparation method of 2-chloro-5-methylpyridine | 宁夏瑞泰科技股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-111333568-B | Selective synthesis method of 2-chloro-5-methylpyridine and 2, 3-dichloro-5-methylpyridine | 江苏扬农化工集团有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-110078660-B | Preparation method of 2-chloro-5-methylpyridine | 江苏扬农化工集团有限公司 | 2021-01-01 | — | — | CN | claimed |
| EP-0108483-B1 | SYNTHESIS OF 2-SUBSTITUTED-5-METHYL-PYRIDINES AND INTERMEDIATES THEREFOR | ICI AMERICAS INC. (US) | 1989-02-08 | — | — | EP | claimed |
| US-4645839-A | Sulphur dehydrogenation process to yield 5-methyl-2-pyridone | ICI AMERICAS INC. (US) | 1987-02-24 | — | — | US | claimed |
| US-4473696-A | Synthesis of 2-substituted-5-methyl-pyridines | ICI AMERICAS INC. (US) | 1984-09-25 | — | — | US | claimed |
| EP-0108483-A2 | Synthesis of 2-substituted-5-methyl-pyridines and intermediates therefor | ICI AMERICAS INC. (US) | 1984-05-16 | — | — | EP | claimed |
| CN-119735565-A | Method for continuously preparing 3-methyl-4-morpholinyl cyclobutanecarboxylic acid methyl ester | 宁夏瑞泰科技股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119707795-A | Preparation method of 2-chloro-5-methylpyridine | 宁夏瑞泰科技股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119118913-A | Preparation method of anti-fibrosis drug pirfenidone | 郑州大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-116987049-A | Method for continuously preparing imidacloprid intermediate 3-methyl-2- (4-morpholinyl) methyl cyclobutanoate | 宁夏瑞泰科技股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116354876-A | Synthesis method of high-purity 2-chloro-5-methylpyridine | 四川大学 | 2023-06-30 | — | — | CN | disclosed |
| US-20220251042-A1 | TOTAL SYNTHESIS OF PIRFENIDONE | Suzhou Fude Zhaofeng Biochemical Technology Co., Ltd (CN) | 2022-08-11 | — | — | US | disclosed |
| EP-0121320-B1 | PREPARATION OF 2-CHLORO-5-METHYLPYRIDINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-08 | — | — | EP | disclosed |
| US-4645839-A | Sulphur dehydrogenation process to yield 5-methyl-2-pyridone | ICI AMERICAS INC. (US) | 1987-02-24 | — | — | US | disclosed |
| US-4612377-A | Preparation of 2-chloro-5-methylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-16 | — | — | US | disclosed |
| US-4584380-A | Synthesis of 2-substituted-5-methyl-pyridines and intermediates therefor | ICI AMERICAS INC. (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0121320-A1 | Preparation of 2-chloro-5-methylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-10 | — | — | EP | disclosed |
| US-4473696-A | Synthesis of 2-substituted-5-methyl-pyridines | ICI AMERICAS INC. (US) | 1984-09-25 | — | — | US | disclosed |
| EP-0108483-A2 | Synthesis of 2-substituted-5-methyl-pyridines and intermediates therefor | ICI AMERICAS INC. (US) | 1984-05-16 | — | — | EP | disclosed |