Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749475 | 0.87 | CHRM3 (0.53) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL10392372 | 0.82 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4153935 | 0.82 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL27963558 | 0.82 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL9295790 | 0.82 | CHRM3 (0.59) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4138872 | 0.81 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL11889628 | 0.80 | KCNH2 (0.50) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL2984162 | 0.79 | CHRM3 (0.56) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL11021099 | 0.79 | MAPT (0.52) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL9426509 | 0.79 | CHRM3 (0.52) | CHRM3CHRM2KCNH2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309424-A2 | New amidino derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |